Hi, The two main problems with that I can sort out are your overweight/Obesity and Lack of exercise. Your job of desk clerk which is sitting job more often might aggravate the situation. Arthritis symptoms might add due to overweight and age, but the muscle problem is bothering you more. I suggest you to do regular walking, staring slowly and regularly and increasing day after day. This should be done by taking regular muscle relaxant tablets under doctor s supervision. You can undergo Bariatric surgery which have long term and better results to reduce your weight and trust me more than half of your problems reduce dramatically after you reduce your weight. So, have a serious thought on undergoing Bariatric surgery by consulting a Bariatric surgeon. It gives promising long term results than Liposuction.