Hi, Progyluton contains both estradiol valerate and norgestrel which is used for decrease pain and blood loss from a certain menstrual condition, vasomotor symptoms associated with the menopause, prevent pregnancy, primary ovarian failure, hypoestrogenism due to hypogonadism, regularization of irregular menstrual cycles which is necessary for a successful pregnancy etc. It is a safe if it is taken according to your doctor s advice. Duphaston contains dydrogesterone which is indicated in women who are trying to conceive if there is proven, documented deficiency of the progesterone hormone during luteal phase. Duphaston is only used in cases of repeated miscarriages. It is used to treat female infertility, various menstrual problems including painful or irregular periods, premenstrual symdrome (PMS) and endometriosis. It should be taken under the supervision of your doctor. HCG shot contains human chorionic gonadotropin (HCG). It is a hormone that supports the normal development of an egg in the ovary of a woman and stimulates the release of the egg during ovulation. HCG shot is used to cause ovulation and to treat infertility in women and to increase sperm count in men. It is only taken as directed by your doctor. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician