Hello! Thanks for using health care magic for asking your question. Klinefelter syndrome with osteoarthritis and depression is surely disabling and i am sure you are having a tough time. However whether your disability illness is under the disability specific illnesses list of your country is something which will decide whether you will get the benefit. Moreover some orthopedics doctor has to quantify your disability before you are certified. Like in India, patient first approaches an orthopedician to quantify his disability and seek a disablity certificate from him. later on he approaches the specific government authority to authorize him for the possible state benefits. So it all depends on the country where you are residing. I hope i was of some help to clarify your doubts. Have a nice day.