I have RA. I have had malignant cancers three times in the last 25 years, testicle at 38 , large right toe removed at 57, bladder cancer at 60. I am now 62 and cancer free. I have taken methotrexate , Enbrel, and predisone for a year now. I have been so stressed about my lowered immune system that I have stopped taking them. My pain is not unbearable. My problem is I am terribly afraid of pneumonia . My doctor says I can get pneumonia from stopping my meds, but they tell me everytime I have an infection to stop my meds? I am prone to having bad sinus infections, and many times they cause me to cough up mucus, and when I call the RA doctor they tell me to skip the meds till the infection is better. My question is isn t this information I am getting somewhat confusing and it stands to reason to me if I need to stop the meds when I have an infection then the taking the meds will contribute to the infection. I think I am better off without the RA meds. I need some clarification, because I have constant sinus infections!