Hi, Thanks for writing in to us. With a delayed or missed cycle and weight gain, the possibility of polycystic ovarian syndrome must first be excluded in you. It may also be that you are perfectly normal and are really pregnant. Let us consider both situations and what needs to be done. 1. If you are possibly pregnant: Please do home pregnancy test at least 15 days after probable unprotected sexual intercourse. There is more than 95% chance that it will confirm a positive pregnancy. 2. To rule out polycystic ovarian syndrome: Symptoms tend to be mild at first. You may have only a few symptoms or a lot of them. The most common symptoms are: Acne. Weight gain and trouble losing weight. Extra hair on the face and body. Often women get thicker and darker facial hair and more hair on the chest, belly, and back. Thinning hair on the scalp. Irregular periods. Often women with PCOS have fewer than nine periods a year. Some women have no periods. Others have very heavy bleeding. Fertility problems. Many women who have PCOS have trouble getting pregnant (infertility). Depression. Most women with PCOS grow many small cysts and the ovaries enlarge in size. That is why it is called polycystic ovary syndrome. The cysts are not harmful but lead to hormone imbalances. This can be seen on ultrasound scan of ovaries and uterus. Hope this helps