Hello. There are some important things that have to be assessed here:
First of all, we have to know if one of the BP medications is a diuretic (A medicine given for high blood pressure
that controls BP by making you urinate more. Examples are: (Chlorothiazide (Diuril) Chlorthalidone Hydrochlorothiazide
(Microzide)IndapamideMetolazone Bumetanide (Bumex)Ethacrynic acid (Edecrin)Furosemide (Lasix)Torsemide (Demadex)AmilorideEplerenone (Inspra) Spironolactone
(Dyrenium). Any of these may be the cause of your frequent urination
It is important to know if the swelling of your ankles is in one ankle and if the shortness of breath
was abrupt (did it start suddenly and are you experiencing chest pain) because tamoxifen use is associated to blood clots that can appear in your inferior extremities and travel to the lung blood vessels. This needs medical assessment right away.
If this swelling is in both ankles and has been progressive (for many weeks and months) and your shortness of breath has gotten worse over months, then this can be a heart issue. In a simpler way, because the heart is what pumps the blood around the body, when it is not able to do so, fluid accumulates in your inferior extremities (swollen ankles) and lungs (shortness of breath). Persistent high blood pressure can be a cause of the heart not being able to work properly. I recommend a cardiology consultation and continue with high blood pressure medications until you are seen by the cardiologist.