Yes, I was recently given a topical cream to use that has a combination of Lidocain 2-48 gm, Ketamine 5.525 mg, Ketoprofen 5.525 mg but also says acetaminophen/ codeine on the side label. I have read some bad things about Ketamine and I am not sure about how much Codeine is in this cream. I understand that the effects of this cream can be intensified by heat?? I just don t see a lot of real solid information about this stuff. My Doctor that prescribed it didn t say much more than it was a new drug cream. I am not sure exactly how much to use. It says a small amount 4 times a day. What if I happen to use a medium amount and I am not sure what that amount is??