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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Bone TB, Histo-pathological Test Showed Scanty AFB, On PZA, INH, Ethmbutol, Rifamin. Recovery Time?

Sir I had a swelling on my left shoulder blade and after surgery it was diagonised with tuberculosis . there was lot of pus in it. Histopathological test said ZN stain-scanty AFB detected. HIV -ve, I started taking (INH, Rif, Ethambutol , PZA). However it was stopped for two weeks because of liver complications, again it started slowly one by one drug. Now it has been 3 months out of which last month is 4 drugs, still continuing 4 drugs. doctor told me atleast 2 months of 4 drugs and then less number. How long it will take for complete cure? Doctors told me its a bone tb. My weight is 65 kg. I am taking 1500 mg of PZA, 300 mg of INH, 1000 mg of EthaMBUTOL and 600 mg of RIFAMCIN.
Mon, 8 Apr 2013
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Pulmonologist 's  Response
Hi shaibalb
thanks fo coming to HCM
you are suffering from tubercular arthritis of left shoulder joint. which is extrapulmonary paucibacillary disease and usually non contagious.

the regimen given by your doctor is as per the guideline which says 2 months of INH,Rif, ethambuto, PZA and following it INH and Rif total duration being 9-12 months in your case.

if acute hepatitis is detected all drugs has to be stopped and then restarted once it resolves to know the culprit drug which are usually INH, Rif and pza....so this was also an excellent step on the part of your doctor...

the daily doses are INH(5mg/kg), Rif(10mg/kg), pza( 25mg/kg) ethambutol (15-20mg/kg)....so you can see the doses are accurate.

it will be my advice and request to kindly continue the treatment for prescribed period and report him if any adverse effect occurs...

best wishes
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Orthopaedic Surgeon Dr. Sathyadharan Panneer's  Response
Anti-TB medications for bone tuberculosis are prescribed for 9-12 months.
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Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.
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Bone TB, Histo-pathological Test Showed Scanty AFB, On PZA, INH, Ethmbutol, Rifamin. Recovery Time?

Hi shaibalb thanks fo coming to HCM you are suffering from tubercular arthritis of left shoulder joint. which is extrapulmonary paucibacillary disease and usually non contagious. the regimen given by your doctor is as per the guideline which says 2 months of INH,Rif, ethambuto, PZA and following it INH and Rif total duration being 9-12 months in your case. if acute hepatitis is detected all drugs has to be stopped and then restarted once it resolves to know the culprit drug which are usually INH, Rif and pza....so this was also an excellent step on the part of your doctor... the daily doses are INH(5mg/kg), Rif(10mg/kg), pza( 25mg/kg) ethambutol (15-20mg/kg)....so you can see the doses are accurate. it will be my advice and request to kindly continue the treatment for prescribed period and report him if any adverse effect occurs... best wishes