Hello dear Understand your concern Yes Primolut N is safe and advisable medicine in PCOD to regularize the menstruation. It should be used long time for about 6 months mainly in second half of cycle to regularize the period. So do not worry, you are on right treatment. Consult the gynecologist and go for following investigation that help in management of case: Reproductive hormone analysis: LH, FSH, prolactin, E2, progestreone, testosterone and DHEAS, USG scan, ovarian follicle study, blood glucose, insulin and lipid profile Doctor may give following advice to cure the PCOS: Tablet metformin: To maintain glucose homeostasis, increase insulin sensitivity and induce ovulation Oral contraceptive pill or progesterone pill: to regularize the period. Flutamide and spironolactone: duretic action and also induce ovulation. Clomiphen citrate can be given to induce ovulation. Topical eflornitine to reduce hirsutism (abnormal hair growth), If medical treatment will not help then surgical process like ovarian dreeling can be done. Diet: avoid excessive sweets and yogurts, avoid spicy and oily food, take small frequent meal rather than large meal, take green leafy vegetables and fresh fruits. Reduce weight by exercise like walking, cycling, running and also do yoga daily in the morning for 45-60 minutes. Reduction in weight by 10 percent cause more induction in ovulation. Hope this may help you Best regards Dr. Sagar