Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

184 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

What is the difference between Pencom injection and Azithral?

Answered by
Dr.
Dr. Rishu Saxena

Cardiologist

Practicing since :2012

Answered : 696 Questions

default
Posted on Wed, 8 Mar 2017 in Hypertension and Heart Disease
Question: what the difference between pencom 12 lac injection and azithral 500 tablate ??
doctor recommended this tablate inplace of injections. because we don't want to take injection.
1 tablate twice of the day for one week and after it 1 in one week.
this tablate is equal to pencom injection ??

pls advice.
doctor
Answered by Dr. Rishu Saxena 31 minutes later
Brief Answer:
Details below!

Detailed Answer:
Hi
Pencom Injection (Benzathine Penicillin) is a long acting antibiotic injection which contains penicillin and treats and prevents a wide range of bacterial infections mostly indicated in valvular heart diseases,while Azithromycin belongs to a group of medicines called azalides which are a sub-class of a group of antibiotics called macrolides.It acts by inhibiting the formation of bacterial proteins. In most organisms this action inhibits cell growth.Erythromycin and drugs of its class like azithromycin are usually given orally for seconadary prevention.
Bioavailability of parentral (i.v) antibiotic is much higer then orally given tablets.So please give your detailed history and attach your 2d echo report for further suggestion.
Thanks
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
default
Follow up: Dr. Rishu Saxena 1 hour later
can we take Azithral 500 tablate inplace of pencom 💉
doctor
Answered by Dr. Rishu Saxena 3 minutes later
Brief Answer:
Yes Azithral can be taken.

Detailed Answer:
Hi again,
Yes you can take azithral 500mg once daily,If you don[t want to go for injectible therapy any more.
Thanks
Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Rishu Saxena 13 minutes later
Dr. have advise to take this tablate twice in a day for one week and after one week, 1 tablet in a week, pls advise
doctor
Answered by Dr. Rishu Saxena 11 minutes later
Brief Answer:
Follow up advice

Detailed Answer:
Hi
According to NCBI trials(U.S. government-funded national resource for molecular biology information centre-
The utility of 500 mg once weekly azithromycin (AZT), an orally effective long-acting antibiotic was evaluated against oral penicillin (phenoxy methyl penicillin 250 mg twice daily) in this study. Forty-eight consecutive patients (44% males, mean age 29.4 years) with established RHD were randomised into two groups-26 patients received AZT and 22 received oral penicillin. Patients were evaluated , at 1 month, 3 months, and 6 months, clinically, serologically and by throat swab culture. End points(results) were absence of streptococcal colonisation, infection or fever at the end of 6 months. During the study, 4 patients (15.4%) in the AZT group developed sore throat and fever, had positive throat culture and positive serology indicating streptococcal infection.None in the oral penicillin group developed streptococcal infection.

Conclusion-weekly 500 mg of AZT is not effective in the prevention of streptococcal throat infection compared to oral penicillin therapy in adult patients with established RHD.

However once in a week schedule is followed in XXXXXXX by some cardiologist,Yet i would suggest you to go either for Erythromycin 250mg twice daily or oral penicillin (phenoxy methyl penicillin 250 mg twice daily).
Please discuss options with your cardiologist.
Thanks.
Above answer was peer-reviewed by : Dr. Prasad
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,  
Drug/Medication ,   ,  

Recent questions on  Sore throat

doctor1 MD

For the past week and a half now I ve been experiencing a growing level of nausea. Shortly after eating it is the worst, but then the nausea generally subsides about 30 minutes to an hour after. It doesn t matter what food type, it s anything I eat. At first when I started having this problem I figured I was getting sick. But I have no other symptoms. No sore throat, coughing, sneezing, or anything like that. I have acid reflux disease, but keep it under control with medication. I ve never had this problem before, and don t understand what it could be. It s really annoying because I have to force myself to eat now, and I ve lost my appetite for almost all foods because I know how I ll feel after eating. It s really stressing me out, and I know I would have to go to a doctor to get a 100% answer, but I can t afford it. I don t eat a lot of junk food, and have actually started eating a lot healthier because I figured it would combat the problem, but it s not doing much. I ve been drinking a lot of fluids also to try and help. When I do drink fluids I don t get nauseas, only when I eat solid food. A couple of months ago I had an ultra sound for gall stones for a completely unrelated problem but there weren t any. Any idea what this might be?

doctor1 MD

I have had a sore throat for about a week and a half now and my sore throat alternates the sides of my throat. It is never at both sides. Also with the sore throat i am getting ear pain. If my sore throat is on the left side my ear pains are on the left side and sometimes with the sore throat and ear pain i will also get a slight headache on the same side also.

doctor1 MD

My father, age 78, is in excellent health and only takes medication for hypercholesterolemia (low 200 s). He recently started Erythromycin for head and chest congestion and sore throat. After taking this for a few days he had blood blisters erupt in his scalp and ears. His head felt a lot of pressure and he was worried he might be having a stroke. His neck and head were stiff with some numbness in his right arm. He DC d the antibiotic and went to his doctor, who placed him on Prednisone. Now he is a little groggy and isn t feeling well so he stopped the Prednisone. He sounds weak and we aren t sure why he was put on the Prednisone. My question is - why take Prednisone if the blisters are drying up? What is the benefit versus the risks?

doctor1 MD

I am writing about my 14 year old son, who has been ill repeatedly 4 times for the past 7 weeks. He s been on antibiotics all 4 times, struggles to recover until his antibiotics are nearly gone, finally feels better for a few days and then gets it again. We are wondering if it is valley fever. Can that come with congestion/sinus symptoms? He s been diagnosed with sinus infections each time, but develops not only significant congestion/sinus symtpoms, but also chest pain, horrible coughing, fatigue, sore throat, and is miserable. He has faithfully taken not only strong antibiotics, but prescription strength cough syrup/decongestant, Flonase nasal spray, Zyrtec once a day, and breathing treatments up to 4 times a day, along with vitamin C and lots of fluids. He is otherwise very healthy, but his doctor is concerned that perhaps it is not really sinus infections he has had. I cannot find on the internet where there is a connection between congestion/sinus symptoms and Valley Fever - curious about that as others have asked if he has been tested for it. We live in Phoenix. As a young child he had repeated ear infections, but 4 years ago at age 10 he had his tonsils and adenoids removed, tubes in his ears, and a major sinus surgery. He has been very healthy ever since until now. Any ideas? Thank you verey much!

doctor1 MD

For the past 3 weeks I have had a very persistent sore throat which at times has made it very difficult to swallow. Lemsips and lozengers ease and alcohol makes it worse. Sleeping can be disturbed due to being painful to swallow. The symptoms seem...

doctor1 MD

I was treated for strep about a month ago. Still have lingering cough . Not bad, but still there. Could this be due to post nasal drip?

doctor1 MD

Temperature 103.1 Very bad sore throat Difficulty swallowing Discolored sputum Chills