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What Causes Painfully Red Blisters Below The Knees While Taking Diabetes Medication?

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Posted on Fri, 10 Feb 2017
Question: I have a red rash on both legs below the knee. It is heavily blistered and has very red areas that are paiiful to the touch. I am a type 2 diabetic and have recently been put onTRESIBA. I HAVE READ THEIR INFO on their reactions. This problem is not highlighted as such. I am also on a smaller dosage of HUMULOG. Is this an interaction? HELP.
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Answered by Dr. Saddiq Ulabidin (1 hour later)
Brief Answer:
It can be due to drug side effects but not likely an interaction

Detailed Answer:
Hi! Welcome to health care magic! Thanks for sharing your concerns with us. We will try to help you in best way possible.

First of all, it is sad to know what you had gone through. Based on the history you have shared, it seems less likely to be a drug interaction as usual approach is to mix long acting insulin with intermediate or short acting like in your case however the tresiba or degludec insulin can cause skin rash or such utricarial reactions however a detailed evaluation by a dermatologist is recommended to rule out any other skin lesion if infective etiology as diabetes itself is immunocompromised state and makes a person prone to viral or fungal infections.

Meanwhile using anti histamines like cetrizine or loratidine may help with itching and analgesics or anti inflammatory drugs like i

buprofen may help with inflammation and pains. Wishing you a speedy recovery. If you have any more questions, feel free to ask. Regards.
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation

Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Saddiq Ulabidin

General & Family Physician

Practicing since :2011

Answered : 3941 Questions

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What Causes Painfully Red Blisters Below The Knees While Taking Diabetes Medication?

Brief Answer: It can be due to drug side effects but not likely an interaction Detailed Answer: Hi! Welcome to health care magic! Thanks for sharing your concerns with us. We will try to help you in best way possible. First of all, it is sad to know what you had gone through. Based on the history you have shared, it seems less likely to be a drug interaction as usual approach is to mix long acting insulin with intermediate or short acting like in your case however the tresiba or degludec insulin can cause skin rash or such utricarial reactions however a detailed evaluation by a dermatologist is recommended to rule out any other skin lesion if infective etiology as diabetes itself is immunocompromised state and makes a person prone to viral or fungal infections. Meanwhile using anti histamines like cetrizine or loratidine may help with itching and analgesics or anti inflammatory drugs like i buprofen may help with inflammation and pains. Wishing you a speedy recovery. If you have any more questions, feel free to ask. Regards.