Question: Hello Doctor. I have a fatty liver problem for the past 4 years now. For the last one year it has become Grade III level. The liver is enlarged and the Doctor said that I need not worry much as I take red/white wine rarely. I was prescribed Udiliv 300 mg twice a day and Librax. I have been having Udiliv for the past 3 years and Librax for the past one year now. I also have the problem of infective colitis and initially I was prescribed O2 and now whenever the stools become loose and if I feel feverish or a bad bowel, he prescribes me antibiotics for a week and I get better. I have been taking Losacar H and Amlodac 5mg for my High BP for the last 11 years now. I also had high cholesterol and have been taking Stator 10mg for the 7 years now. I eat non vegetarian, primarily fish followed by chicken and occasionally red meat. I also occasionally drink a glass or two of red wine or white wine. I do not do regular exercise due to travel and late night working. All this while my tst always showed that everything is under normal levels and my BP is always under control. I had a skin problem on my right foot (near my heel) for a long time and recently the itiching was severe hence I met a skin specialist and he did a biopsy of that part and the report showed as psoriasis. The Doctor had asked me to test CBC, SGPT & SGOT before starting my treatment and at that time all were at normal levels. I was prescribed Methotexrate, once a week, initially 5mg, then 10 mg and later increased to 15 mg. I am taking this medicine for the past 12 weeks now. Three days back I did my LFT and found that the SGPT has gone up to 66. SGOT is within normal levels and all other readings are also under normal levels. One of my known Doctor said that Methotexrate is immunosuppresent drug and this could be cause of elevated SGPT levels. Since I have fatty liver Grade III and now the SGPT also going up to 66. I need your advise on how to about with this status. what should be my further course of action? Should I continue this treatment? and how can I control my fatty liver condition and bring SGPT to normal levels?

Dear Doctor Thanks for your guidance. I have few more queries, Please help me. 1. Is the fatty liver due to medication or due to intake of atorvastatin? 2. Can I have very occasionally a glass of redwine or whitewine? I am in sales & marketing field and occasionally I may have to give company for few of my clients. 3. Will Hepa Merz help to reduce fat in Liver or for what is this medicine taken? 4. Can I take chicken and fish in my diet? 5. Should I stop taking Librax and how does this medication help? 6. Does Methotrexate affect the Liver? I will certainly start my exercise and also meet a dietician to chart my diet. Thank you. Regards XXXXX