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Does Emotional Stress Elevate DHEA-S?

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Posted on Wed, 11 Feb 2015
Question: Can long term enotional stress slightly elevate DHEA-S?
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Answered by Dr. Vivek Chail (34 minutes later)
Brief Answer:
Long term emotional stress less likely to elevate DHEAs

Detailed Answer:
Hi XXXX
Thanks for writing in to us.

I have read through your query in details.
There has been medical research to evaluate the "Study of the stress response: role of anxiety, cortisol and DHEAs" done by researchers in the recent past.

As per their results, the worriness and the underlying anxious ruminations and negative anticipations, which characterize trait anxiety, were less important in subjects who increased plasma DHEAs levels. In addition, emotional tension and uneasiness, which accompanies state anxiety, were also less marked.

It has also said that many authors have proposed a beneficial action of DHEA on the feeling of well-being. This beneficial role could be related to a double action of DHEA: a direct effect provided by its transformation into sexual hormones, an indirect one mediated by its competition with cortisol, of which the synthesis and consequently the activity decrease.

Therefore we can see from review of medical literature that long term emotional stress or anxiety is less likely to elevate DHEAs.

Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Vivek Chail (45 hours later)
What are causes for elevation of DHEA-S ? All other hormone testing was normal (LH,FSH,Prolactin,insulin)
doctor
Answered by Dr. Vivek Chail (12 minutes later)
Brief Answer:
Up to 600 mcg/dL above normal upper limits is acceptable

Detailed Answer:
Hi XXX
Thanks for writing back with an update.

Increased DHEAs is indicates increased adrenal androgen production. Levels up to 600 mcg/dL above normal upper limits can be seen for no particular identifiable reason and is acceptable. Should there be a rise of more than 600 mcg/dL then a cause in the adrenal glands might be suspected.

As yours is about 400 (?mcg/ dL) above normal then there is no concern.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Vivek Chail

Radiologist

Practicing since :2002

Answered : 6874 Questions

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Does Emotional Stress Elevate DHEA-S?

Brief Answer: Long term emotional stress less likely to elevate DHEAs Detailed Answer: Hi XXXX Thanks for writing in to us. I have read through your query in details. There has been medical research to evaluate the "Study of the stress response: role of anxiety, cortisol and DHEAs" done by researchers in the recent past. As per their results, the worriness and the underlying anxious ruminations and negative anticipations, which characterize trait anxiety, were less important in subjects who increased plasma DHEAs levels. In addition, emotional tension and uneasiness, which accompanies state anxiety, were also less marked. It has also said that many authors have proposed a beneficial action of DHEA on the feeling of well-being. This beneficial role could be related to a double action of DHEA: a direct effect provided by its transformation into sexual hormones, an indirect one mediated by its competition with cortisol, of which the synthesis and consequently the activity decrease. Therefore we can see from review of medical literature that long term emotional stress or anxiety is less likely to elevate DHEAs. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements. Hope your query is answered. Do write back if you have any doubts. Regards, Dr.Vivek