HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Does Medroxypogesterone Cause Cushing Syndrome?

default
Posted on Thu, 6 Mar 2014
Question: I am 22, i used meprste for irregular period which was prescribed by doc bt since d day i started using i find many changes in me,gained weight ,felt uneasy,fatigue,countious periods after stopping meprate nd even symptoms like cushing syndrome .wt shud i do to reverse the side effects ??plzzzzzzz suggest me i hve my wedding on 20 of this month nd i cnt consult a doc nw . Plzzzz plzzzz help me, m scared
doctor
Answered by Dr. Sree Gouri SR (1 hour later)
Brief Answer: Better to get evaluated Detailed Answer: Hi, Thanks for the query. Meprate contains medroxypogesterone. It can cause side effects like weight gain, mood swings, fatigue etc. Cushing syndrome due to using medroxypogesterone for short period is very rare. After stopping medroxypogesterone, withdrawal bleeding can occur. But having bleeding for 4 weeks is somewhat abnormal. Better option is consulting gynecologist and endocrinologist and getting evaluated. By undergoing ultrasound, thyroid profile, 24 hours cortisol levels etc investigations, the possible cause for your problem can be identified and treated. If you cannot consult doctor now, you can follow below measures: - If you are having bleeding now, take pausemf as advised by your previous doctor to control the bleeding. If bleeding doesn't control with that better to consult gynecologist to get evaluated. -If there is no bleeding, no need to worry. Half Life of meprate is 15 to 17 hours. So gradually the drug will be eliminated from the system. And side effects will decrease. To stretchmarks you can use topical creams containing Aloe Vera and vitamin E. Use iron supplements to treat possible anemia. -Try to do exercises to decrease the weight. Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the response, please give your review at the end of the discussion. Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Sree Gouri SR (18 minutes later)
Can we get stretch marks wider nd will it lead to getting thin of skin nd i can see my nerves very clearly, why is it?? Nd m getting acne on my face.All these started only after medication. And wt could be the reason of bleeding? I hve taken meprate for 21 days nd in d mean while i missed takin meprate for 3 to 4 times nd i dint take it in d appropiAte timings.and can cushing syndrome can b a side effect of using meprate nd if so vil it go???
doctor
Answered by Dr. Sree Gouri SR (3 hours later)
Brief Answer: Hormonal imbalance Detailed Answer: Hi, Increasing weight can lead to accumulation of fatty tissue. That can lead to stretching and separation of collagen fibers and formation of stretch marks. In fair complexion individuals vessels can be seen underneath the stretched skin. Hormonal imbalance, stress and strain can lead to acne formation. Missing the pills and altering the time of intake of pills can lead to withdrawal bleeding. But having bleeding continuously for 4 weeks is somewhat abnormal and needs evaluation. Menorrhagia can be seen due to many causes like hormonal imbalance, thyroid hormonal abnormalities, structural causes like fibroids etc. Regarding Cushing syndrome we can come to one conclusion only after investigations. Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Sree Gouri SR (2 hours later)
Thank yu soooo much doc!!!!!!! Nd m sorry for askin 1last question do strech marks occur wider nd in pink colour
doctor
Answered by Dr. Sree Gouri SR (1 hour later)
Brief Answer: Yes Detailed Answer: Hi, Yes. Stretch marks can appear in pink color and gradually the color may change also. The size of the marks depends on the extent of stretching of the skin. You can see in examples in below link. WWW.WWWW.WW Take care.
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sree Gouri SR

OBGYN

Practicing since :2006

Answered : 5839 Questions

Ask me a question
premium_optimized

The User accepted the expert's answer

Ask a Gynecologic Oncologist
Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
backtotop2
Does Medroxypogesterone Cause Cushing Syndrome?

Brief Answer: Better to get evaluated Detailed Answer: Hi, Thanks for the query. Meprate contains medroxypogesterone. It can cause side effects like weight gain, mood swings, fatigue etc. Cushing syndrome due to using medroxypogesterone for short period is very rare. After stopping medroxypogesterone, withdrawal bleeding can occur. But having bleeding for 4 weeks is somewhat abnormal. Better option is consulting gynecologist and endocrinologist and getting evaluated. By undergoing ultrasound, thyroid profile, 24 hours cortisol levels etc investigations, the possible cause for your problem can be identified and treated. If you cannot consult doctor now, you can follow below measures: - If you are having bleeding now, take pausemf as advised by your previous doctor to control the bleeding. If bleeding doesn't control with that better to consult gynecologist to get evaluated. -If there is no bleeding, no need to worry. Half Life of meprate is 15 to 17 hours. So gradually the drug will be eliminated from the system. And side effects will decrease. To stretchmarks you can use topical creams containing Aloe Vera and vitamin E. Use iron supplements to treat possible anemia. -Try to do exercises to decrease the weight. Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the response, please give your review at the end of the discussion. Take care.