Brief Answer:
Current dose is unlikely to help in
depression.
Detailed Answer:
Hi,
Welcome to Healthcare Magic!
The dosage of
trazodone you are taking is unlikely to bring you any improvement in depressive symptoms. For antidepressant action, trazodone needs to be prescribed in dosage of around 250 to 600 mg per day. In dosage less than 100 mg, it just helps in insomnia. The same is true for
quetiapine. A dose of 25 mg quetiapine will just improve your sleep, but not have any significant effect on other symptoms. One fourth of the 25 mg tablet can therefore be expected to have even lesser effect. For any other therapeutic benefits, dosage of more than 300 mg per day is needed. I also would like you to know that quetiapine is not an antidepressant, but primarily an
antipsychotic that has been found useful in bipolar depression in addition to its usual indications which are
schizophrenia and mania.
Since whatever you have been prescribed is only for insomnia, in my opinion, you should ask your doctor for medicines to treat your anxiety disorders (OCD, GAD, Panic disorder and mild PTSD). A medicine of the SSRI class (
fluoxetine,
sertraline etc) would be a good choice and would help in all these disorders. Once your anxiety and depression improve, you will see an improvement in sleep as well and then you will not need to depend on other medicines for insomnia.
What I wish to convey is that insomnia is a result of your anxiety disorders and just treating will not solve the problem. But treatment of your anxiety disorders can solve your sleep related problems.
Hope this clears up things for you. Please feel free to ask if you need any clarifications.
Best wishes.
Dr Preeti Parakh
MD Psychiatry