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Can MePrate Be Used To Increase Progesterone?

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Posted on Wed, 12 Jan 2022
Question: Can MePrate 10 mg be used to increase progesterone in my case where Estradial to progesterone ratio is around 780:1 ? Will is worsen my estrogen dominance ? Bloodwork: Prolactin 31.80 ng/ml, Estradial E2 157.00 pg/ml, progesterone 0.2 ng/ml, Also have hypothyroidism 50 mcg Eltroxin, Stress is there
doctor
Answered by Dr. Deepti Verma (19 hours later)
Brief Answer:
Meprate not given for progesterone supplementation

Detailed Answer:

Hi,

Meprate is not given for progesterone supplementation, especially if you are trying to conceive.
The progesterone preparations given are natural micronised progesterone like susten, gestin, lupigest etc.
Progesterone supplementation is given cyclically and it will not worsen your estrogen predominance.
Hope you found the answer helpful.
Regards
Dr Deepti Verma
OBGYN
Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Deepti Verma (17 minutes later)
Dear Dr

Thank you very much for your reply. I am not trying to conceive.

So this MePrate won't increase my progesterone ?
The purpose it is given is to reduce estrogen dominance.

Should I go for natural ones if MePrate won't increase progesterone ? If so , will the natural ones worsen estrogen dominance.

I had heavy bleeding in last two periods and having breast tenderness.

I think Meprate causing headache.

I also read somewhere that prolactin is also a measurement for estrogen dominance as it indicates estrogen presence in tissues cells etc. mine has come quite high. Read normal is upto 12..

The readings were taken about 4 days after period
doctor
Answered by Dr. Deepti Verma (9 hours later)
Brief Answer:
Meprate not used

Detailed Answer:
Hi dear,
Estrogen predominance can be regularized by micronised progesterone in the second half of the cycle.
Prolactin levels are borderline increased.
If your periods are delayed or irregular, then treatment to reduce prolactin is advised.
Cabergoline is given for reducing the prolactin levels.
Meprate is not given in fertility treatment.
Please elaborate how regular is your menstrual cycle, so I can suggest you further.
Regards
Dr Deepti Verma
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Deepti Verma (13 hours later)
Dear Dr

Yes my periods haa be been irregular. Last two periods especially were quite close with heavy bleeding cramping.

They have been irregular on periods for a while

I'm not taking fertility treatment. Meprate is given to reduce estrogen dominance.

Thank you.
doctor
Answered by Dr. Deepti Verma (23 hours later)
Brief Answer:
Susten or Gestin

Detailed Answer:
Hi dear,
Meprate can lead to congenital anomalies in the fetus, if taken in first trimester.
Therefore, meprate is not used in fertility management. It is given to regulate the periods, when fertility is not an issue.
Tablets such as Susten or gestin should be used in fertility treatment.
Regards
Dr Deepti Verma
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Remy Koshy
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Answered by
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Dr. Deepti Verma

OBGYN, Maternal and Fetal Medicine

Practicing since :2009

Answered : 5064 Questions

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Can MePrate Be Used To Increase Progesterone?

Brief Answer: Meprate not given for progesterone supplementation Detailed Answer: Hi, Meprate is not given for progesterone supplementation, especially if you are trying to conceive. The progesterone preparations given are natural micronised progesterone like susten, gestin, lupigest etc. Progesterone supplementation is given cyclically and it will not worsen your estrogen predominance. Hope you found the answer helpful. Regards Dr Deepti Verma OBGYN