What is Estrogen?

Estrogens or oestrogens (see spelling differences) are a group of compounds named for their importance in both menstrual and estrous reproductive cycles. They are the primary female sex hormones. Natural estrogens are steroid hormones while some synthetic ones are non-steroidal. The name comes from the Greek ' (oistros), literally meaning "verve or inspiration" but figuratively sexual passion or desire, and the suffix -gen, meaning "producer of".

Estrogens are synthesized in all vertebrates as well as some insects. Their presence in both vertebrates and insects suggests that estrogenic sex hormones have an ancient evolutionary history.

Estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for postmenopausal women, and in hormone replacement therapy for trans women.

Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen receptors which in turn modulate the expression of many genes. Additionally, estrogens bind to and activate rapid-signaling membrane estrogen receptors, such as GPER (GPR30).

Questions and answers on "Estrogen"

Are there any studies on women who have been diagnosed with early, stage 1 ER/PR positive breast cancer (neg nodes) and have decided to go on low...

doctor1 MD

Thank for asking to HCM
I really appreciate your concern and I would like to say that up till now lot of research and work done on breast cancer...

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hello doctor , i am 46, female and my periods stoped a couple of years ago. i am finding difficulty while participating in intercourse. i am...

doctor1 MD

Thanks for the query
You get get rid of the dryness by using a lube. Durex Makes 'play' which is of good enough. Estrogen therapy can be used buy it...

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I am 60 years old and my vaginal opening is smaller how can I expand the vagina it is so painful in hurts to bad to have sex. I have bought the...

doctor1 MD

Hello, I would be happy to help you with your question.

Here is what I would recommend:

1. Start some vaginal estrogen (available from your doctor...

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