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Can Amoxicillin Cause A Persistent Rash?

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Posted on Thu, 2 Jul 2015
Question: Prescribed Clorithmyc, Amoxycillin, Omeprizole for h. pylori. Doc said stop Clarithromycindue to rash, continue Amoxycillin. Still have rash. Could it be Amox?
doctor
Answered by Dr. Drkaushal85 (30 minutes later)
Yes, amoxicillin can cause rash. So avoid it and start antihistamine.
Please hit thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Drkaushal85 (1 hour later)
Should i to er for rash
doctor
Answered by Dr. Drkaushal85 (1 hour later)
Brief Answer:
Better to start antihistamine drug.

Detailed Answer:
Thanks for your question on Health Care Magic.
Please let me know
1. Exact site of rashes?
2. Are they itching?
3. Are they red and swollen?
Usually drug rashes subside with stoppage of offending drug and starting antihistamine drugs.
Please reply me answers of above asked questions, so that I can guide you better.
I will be happy to help you further.
Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Drkaushal85 (9 hours later)
Thats what the rash looks like. It is only very slightly itchy, more so of a flushed heat feeling than anything else. Have taken Benadryll yesterday and today and took a oatmeal baking soda bath. Sumptoms seem to be relieved somewhat but not all the way. I was on Clarithromycin with Amoxycillin for h pylori. Doctor told me to stop both and gave me a steroid for the rash. I dont understand. Ive taken Amoxycillin before and was all right, although this time my dosage is 2000mg a day, 2 pills twice a day. Ive never taken the Clarithromycin before so i think that was the culprit but not sure. Thanks for any insight .
doctor
Answered by Dr. Drkaushal85 (54 minutes later)
Brief Answer:
Clarithromycin is more likely culprit drug.

Detailed Answer:
Thanks for your follow up question on HCM.
I can understand your concern.
By your history and description, possibility of clarithromycin induced rashes is more.
And you are improving with mostly benadryl.
It is having antihistamine drug. This is treatment of choice for drug induced rashes.
Amoxicillin at high doses can also cause skin rashes.
So it is very difficult to identify the culprit drug in your case.
Please let me know
1. Do you have any kind of allergies?
2. Do you have similar kind of skin reaction in the past?
Please reply me answers of above asked questions, so that I can guide you better.
I will be happy to help you further.
Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Drkaushal85 (9 hours later)
No i have never had this sort of reaction to antibiotics before. The only minir issue ive ever had was on a 5 day treatment with Zythromax where i got a slight rash on my right forearm that quickly went away when i finished the drug. My doctor told me to stop both Clarithromycin and Amoxycillin and did tell me to take 2-25mg Benadryll every 4 hours. They also put me on Methylprednisolone 21-4mg pills for 6 days. Tapering by one pill a day. Is this Methylprednisoline safe? Are side effects bad on a 6 day treatmemt? Or are they just minor side effects? Thank you for your help .
doctor
Answered by Dr. Drkaushal85 (3 minutes later)
Brief Answer:
No need to worry for side effects in 6 days tapering steroid course.

Detailed Answer:
Thanks for your follow up question on HCM.
I can understand your concern.
No need to worry for tapering course of steroid over 6 days. It will not any long term side effects like hypertension, osteoporosis, diabetes etc.
Short term side effects like gastritis is common.
So drink plenty of fluids orally. Avoid stress and tension. Avoid hot and spicy food.
Finish your benadryl and steroid course.
You will mostly improve.
Hope I have solved your query.
If you are not having further queries, then please close the conversation and rate my answer.
You can ask me directly on bit.ly/askdrkaushalbhavsar.
Wish you good health. Thanks.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Drkaushal85

Pulmonologist

Practicing since :2008

Answered : 15005 Questions

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Can Amoxicillin Cause A Persistent Rash?

Yes, amoxicillin can cause rash. So avoid it and start antihistamine. Please hit thanks.