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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Weight Loss Be A Side Effect Of Taking Paxil For Long Term ?

I have been supervised by doctor in getting off of Paxil CR. I had been on 37.5 mg everyday for 6 months (gradually increased to that dose). As my personal situation changed, I felt I wanted off the Paxil as it had served it s purpose. Doc suggested to go from 37.5 to 25 to 12 mg over a couple weeks, then a 12 mg every other day for 2 weeks. I fould that when I had the 12 mg dose, I started having what I felt were small adrenalin spikes (shocks) that were uncomfortable. I described them to the doctor as small random electrical impulses in my brain . He called it Adrenalin Shocks and suggested a couple of therapies. 1. If I wanted to remain off of the Paxil, he would give me a prescription of .5mg of Xanax to help deal with the anxieties of the shocks, or 2, I could go back on the Paxil CR, which I didn t want to. He said the longest he s seen someone suffer from these after getting of of the Paxil was 6 months and that they should dissipate over time. It s been 3 weeks and it is somewhat lesser of an event for me, but still bothers me. I just take the Xanax before bed to help get my mind calmed down for sleep and don t take it everyday. I will also say, over the last 4 months, I have lost 40 pounds, exercise more and do not have high blood pressure or high chlorestorol either. I m going in for a complete physical here in another 3 weeks, but has anyone heard of this as a side affect? Is it really going to be up to 6 months?
Fri, 18 Feb 2011
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Psychiatrist 's  Response
Hi

Yes electrical shock like sensations are known withdrawal effects of Paroxetine.
The duration of these is dependent on individual body and is not predictable, unfortunately, as with any other withdrawal effect.

Since for the past one month you are experiencing a decrease in their frequency, its a good sign that they will go off eventually but again, when is not predictable.

Hope this helps
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Can Weight Loss Be A Side Effect Of Taking Paxil For Long Term ?

Hi Yes electrical shock like sensations are known withdrawal effects of Paroxetine. The duration of these is dependent on individual body and is not predictable, unfortunately, as with any other withdrawal effect. Since for the past one month you are experiencing a decrease in their frequency, its a good sign that they will go off eventually but again, when is not predictable. Hope this helps