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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Which Liver Enzyme Is Associated To Cancer?

My husband has an elevated liver enzymes. One of which was more the double what is normal not sure which one it was a number of 18 and normal is 8 I believe. Now an MRI will be scheduled and then biopsy? What is that enzyme test not an alt or ast. The word cancer was mentioned. It s upsetting to say the least
Mon, 1 Dec 2014
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Pulmonologist 's  Response
Thanks for your question on HCM.
In my opinion enzymes other than ALT and AST , which suggest malignancy are
1. GGT (Gamma Glutyl Transferase)
2. ALP (Alkaline Phosphates).
GGT is elevated if tumour in liver causes obstruction in the billiary system.
ALP is again raised in liver cancers as it is produced by liver.
So mostly these two enzymes are responsible for probability of malignancy in your husband's case.
Better to get done CT or MRI and guided biopsy. As biopsy is the diagnostic test for malignancy.
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Which Liver Enzyme Is Associated To Cancer?

Thanks for your question on HCM. In my opinion enzymes other than ALT and AST , which suggest malignancy are 1. GGT (Gamma Glutyl Transferase) 2. ALP (Alkaline Phosphates). GGT is elevated if tumour in liver causes obstruction in the billiary system. ALP is again raised in liver cancers as it is produced by liver. So mostly these two enzymes are responsible for probability of malignancy in your husband s case. Better to get done CT or MRI and guided biopsy. As biopsy is the diagnostic test for malignancy.