Hello doctor , My issue is some thing different , my total muscle mass got reduce gradually form 6 month it got thinner i can find in my mouth its so soft before it was thick mean ton got reduce , and when i open my mouth it is expanding very freely over elasting mouth joints or not tight i can fee this muscle thinner allover the body my stomach muscle so thinner , chest muscle mass got reduce like water packet like without thick fat ) its very unthick ... and my buttock muscle also got week like unthick fat some thing fat are spreading not combine , my anus part is expand little free its not thight , and my pelvic palce under scrotum muscle like muscle free like not muscle its not tight as well , my neck is not strenghten as well flabbyness moving very freely normally it will be tight for me its is expanding ... and my skin tone is also reduced so provide your detailed explanation i will tell what are the studies i done i cant past all the report detail so please tell the detail . 1. I have done EMG its normal with out issue , and cpk test no muscle loss around 60 to 50 out of 140 ,ESR is normal , CRP is normal , RA is negative ,ana is negative . only i have vitamin D defeciency i taking 60k iu weekly once seems its not the issue cause . 2. Nerve condition study seems some weekness in right hand but i have able to move with out issue , but all the body joints or very free its not in tight position .. 3. MRI brain is normal , whole spain buldge it l5 to s1 and l4 to l5 , but i check with bone doc he told its not the issue cause . 4. check with romatoide doctor he took , RA,ANA, renal profile , iron , calcium all normal ...jut he is saying all right gave calcium tablet... 5. neuro doctor said issue not reated to neuro .. but he dint checked my pelvic as well under scrontam i feel the tone is very low in the above part .... penis muscle tone is little thinner compare to before .ever all over my body not like manly skin with rought and thick its so soft .and waterly ... 6. RBC is normal only wbc is little hight around 12k maide be throught infection he told . 7 . usg scan normal ,, 8. i have done 24 hours urin protine its also 9% .. 9. hormone no hypo thyroide , pth is normal , only cortisol is high 29 outof 19 in the morning with out striod medicie during night then go to test on morning i took... 10. When i touch my check i can see the layer and fat is very water like unthick ... 11. my penis muscle tone also reduce and thinner as well my pelvi and buttock and neck muscle tone reduce not in streanght . 11. my GGT is high sgpt is 80 , sgot is 37 due to took medicine taken mide be so doctor ask to take udiliv 300 so im taking past 8 days i dont have drinking habit and smoking habit ....as week feel while have food pasage is week so they have sugged vitamin E taking 2 day i fee better while have food . Note : so please study in detail and provide the cause of issue ... main thing is muscle is not thicker its was happend past 6 month and body are so week and skin on neck and under bottom of butock also elastic not tight like pushing rubber band .. Note: before endocrine doc ask to take test for cortisol he told to take 11 pm medicine and take test in morning at 8 .. so the medicne prescribe is setroide it may affect my muscle issue .