Hello sir, my ESR is 120, CRP is 98 and HLA B27 is positive. So doc suggested me to take 1. Saaz 500 mg 2times a day, Naproxen 500mfg 2 times a day, Methotrexate 15mg once a week, folic acid 5mg once a week and depo-medrole inj 80mg once a week for 4weeks. I have been taking this course for more then 1 month but there is no relief from cronic pain in both knees, ankles of both legs and middle finger with heavy swelling. So plz suggest me what should I do. Thanks and regards - Sachin