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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Difference Between Tropan And Trofame?

my father (82 yrs) has frequent uncontrollable urination problem. He has been prescribed Tropan-5, which was later changed to Trofame. This did not solve the problem, though it MAY have improved the situation if they hadn t been taken. He also possibly has glaucoma and is going for tests for this next week. My question - (1) What is the difference between Tropan & Trofame ? (2) if he DOES have glaucoma, then what is the alternate to tropan/ trofame ?
Tue, 2 May 2023
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General & Family Physician 's  Response
Hi,

Tropan (generic name: oxybutynin) and Trofame (generic name: tolterodine) are both medications used to treat urinary incontinence, urgency, and frequency in patients with overactive bladder. However, they belong to different classes of drugs and have some differences in their mechanisms of action and side effects.

Tropan belongs to a class of drugs called anticholinergics, which work by blocking the effects of acetylcholine, a neurotransmitter that plays a role in bladder muscle contractions. By blocking acetylcholine, Tropan helps to relax the bladder muscles and decrease urinary urgency and frequency. Tropan can cause side effects such as dry mouth, constipation, blurred vision, dizziness, and confusion, especially in older adults.

Trofame belongs to a class of drugs called antimuscarinics, which work by blocking the effects of acetylcholine on specific receptors in the bladder. By blocking these receptors, Trofame helps to reduce bladder contractions and decrease urinary urgency and frequency. Trofame can also cause side effects such as dry mouth, constipation, blurred vision, and dizziness.

If your father is diagnosed with glaucoma, he should avoid anticholinergic medications like Tropan and Trofame, as they can worsen the condition by increasing intraocular pressure. In such cases, other medications can be used to treat overactive bladder, such as mirabegron, which works by activating beta-3 receptors in the bladder to relax the smooth muscle and increase bladder capacity. Your father needs to discuss his medication options with his healthcare provider, taking into account his medical history and any other medications he is taking.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Priyanka, General & Family Physician
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What Is The Difference Between Tropan And Trofame?

Hi, Tropan (generic name: oxybutynin) and Trofame (generic name: tolterodine) are both medications used to treat urinary incontinence, urgency, and frequency in patients with overactive bladder. However, they belong to different classes of drugs and have some differences in their mechanisms of action and side effects. Tropan belongs to a class of drugs called anticholinergics, which work by blocking the effects of acetylcholine, a neurotransmitter that plays a role in bladder muscle contractions. By blocking acetylcholine, Tropan helps to relax the bladder muscles and decrease urinary urgency and frequency. Tropan can cause side effects such as dry mouth, constipation, blurred vision, dizziness, and confusion, especially in older adults. Trofame belongs to a class of drugs called antimuscarinics, which work by blocking the effects of acetylcholine on specific receptors in the bladder. By blocking these receptors, Trofame helps to reduce bladder contractions and decrease urinary urgency and frequency. Trofame can also cause side effects such as dry mouth, constipation, blurred vision, and dizziness. If your father is diagnosed with glaucoma, he should avoid anticholinergic medications like Tropan and Trofame, as they can worsen the condition by increasing intraocular pressure. In such cases, other medications can be used to treat overactive bladder, such as mirabegron, which works by activating beta-3 receptors in the bladder to relax the smooth muscle and increase bladder capacity. Your father needs to discuss his medication options with his healthcare provider, taking into account his medical history and any other medications he is taking. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician