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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Lowering Of PSA Level After Having Seed Implant?

I had prostate cancer 3 1/2 years ago Gleason 3+4 =7 PSA 4.3 cancer contained in 1/2 of prostate no spreading. I elected seed implant For the next 3 1/2 years PSA never dropped but rose to over 7. Doctor was examining alternatives as he thought the seed implant failed... He was on vacation so I ran the PSA one more time and WOW! it shows a drop to we might have done something unnecessarily if I did not run the PSA . I know ther are bounces.. but a drop that fast. Is that possible and maybe some idea why and how Steve
Wed, 3 Oct 2018
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General Surgeon 's  Response
Hi,

The prostate seed implant is a type of Brachytherapy or radio iodine therapy for prostate malignancy. As it reacts upon the cancer cells of prostate and kills them, definitely the tumor marker in terms of PSA level will fall down as a result of positive effect of the same only.

In my opinion, the seed implant is working fine and perfect, there does not sound to be any other problem to think about its failure.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Bhagyesh V. Patel,
General Surgeon
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What Causes Lowering Of PSA Level After Having Seed Implant?

Hi, The prostate seed implant is a type of Brachytherapy or radio iodine therapy for prostate malignancy. As it reacts upon the cancer cells of prostate and kills them, definitely the tumor marker in terms of PSA level will fall down as a result of positive effect of the same only. In my opinion, the seed implant is working fine and perfect, there does not sound to be any other problem to think about its failure. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon