Hi, The symptoms you described, such as memory loss, loss of concentration, depression, anxiety, and difficulty coping, could be caused by several factors. Here are a few possible causes: - Stress: Chronic stress can cause mental fatigue, difficulty concentrating, and memory problems. It can also trigger depression and anxiety. - Depression and anxiety: Both depression and anxiety can cause memory problems, difficulty concentrating, and other cognitive impairments. These conditions can also affect sleep patterns, appetite, and energy levels. - Sleep disorders: Sleep disorders, such as insomnia or sleep apnea, can cause fatigue, irritability, and difficulty concentrating. They can also affect memory and cognitive function. - Hormonal imbalances: Hormonal imbalances, such as those that occur during menopause or thyroid disorders, can cause cognitive impairments, including memory loss and difficulty concentrating. - Nutritional deficiencies: Deficiencies in certain nutrients, such as vitamin B12, can cause memory loss and cognitive impairments. It is important to talk to a healthcare professional about your symptoms to determine the underlying cause and appropriate treatment plan. A healthcare professional may recommend a physical examination, blood tests, or other diagnostic tests to identify any underlying medical conditions. Treatment may involve a combination of these approaches like medication, therapy and lifestyle changes. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician