My mother-in-law has undergone surgery for breast cancer and is being treated for fluid collection (tapping is being done and thoracoscopy is being considered) after first chemo. She is admitted in one of the known hospitals in Mumbai. Can Dr. Agarwal help us? Our doctors do not understand why the fluid is being collected. PET scan was done and no cancer was detected. Please advise. Case history: 1.Breast cancer was detected in August 2011 when Mammography was done 2.Surgery (lymph node dissection in right breast) done on 31st August 2011; she was fit without any complications 3. Chemoport insertion done on 19th September 2011; no noticeable complications 4.     During the first Chemotherapy on 20th September 2011, she developed some complications a.     Test dose and another drug were given through Chemoport and she had no problems b.     While the third medicine (in red colour) was injected through Chemoport, she had uneasiness / gastric-like discomfort and short-breath. This started 10-15 minutes after the medicine started. Immediately this medicine was stopped and medicines to control gastric discomfort was given. After a couple of hours, when her condition became normal, remaining quantity of the red medicine was injected. Immediately after the medicine got finished in around 15 minutes, she again developed breathing problems and uneasiness. Rest of the medicines were not given and she was kept under observation. c.     She was normal the next day and rest of the chemo medicines (one bottle + a push up drug) were administered through I.V. She was discharged from the hospital after few hours. d.     Once reached home, she developed gastric-like problems and short-breath. On the 2nd day she had severe breathlessness and her stomach started bloating. e.     She was taken to the hospital on 23rd and around 2.5 liters of fluid was removed from both sides of the body by tapping. Her condition improved. f.     After 2 days (on 25th), she again felt breathlessness and tapping was done again and around 1.3 liters of fluid was removed. g.     On 2nd October, when she had mild breathlessness, tapping was done again and around 2.2 liters of fluid was removed. 5.     PET Scan was done on 29th September 6.     Doctors are unable to tell us why and how the fluid is getting accumulated. No growth was found in the fluid so far. 7.     A Thoracic surgeon inspected her and advised thoracoscopy after her WBC count increased (currently it is low). He said thoracoscopy could be done on right side now and left after 3 months.