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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Symptoms Of Thalesimia Trait?

Could the undermentioned response be due to Thalesimia Trait? as the pesrosn the question was asked for was diagnosed as having a Thalasemia trait. the following is an additional report, please suggest: PLATELET DISTRIBUTION WIDTH(PDW) 16.97 fL 9.6-15.2 MEAN PLATELET VOLUME(MPV) 11.7 fL 6.5-12.0 PLATELET COUNT 188 X 10³ / μL 150-400 The C reactive protein is also high, which is 3.21 where as the cholesterol level ( all - HDL/LDL/VLDl ) are normal. Your comments and suggestions please PLATELET TO LARGE CELL RATIO(PLCR) 36 % 19.7 - 42.4 PLATELETCRIT(PCT) 0.26 % 0.19 - 0.39 Hi, thanks for using healthcare magic A full blood count provides information on the hemoglobin, the white cell count and its breakdown of the types of white cells, platelet count, the structure or shape of the red blood cells present, the intensity or colour of the red blood cells. Anisopoikilocytosis- this means red blood cells of different shapes and sizes The term normocytic means that the red blood cells are of normal size, microcytic means that they are smaller than normal. Normochromic means that there is a normal concentration of hemoglobin in the red blood cell, hypochromic means that the concentration is decreased. Anemia/low red cell mass (with a low hemoglobin) is classified as (1)normochromic, normocytic anemia ( 2) microcytic hypochromic anemia (3) macrocytic anemia. The most common cause of microcytic hypochromic anemia is iron deficiency, though there are other causes. Futher investigations would normally involve checking serum iron and total iron binding capacity- these would determine if the cause is iron deficiency or otherwise. Iron deficiency is often due to small unnoticable amounts of blood loss and if this is found , there will be other investigations to be done. An elliptocyte is an oval to cigar shaped red blood cell which is seen in some types of anemia such as iron def anemia. They are also called ovalacytes. 15% or less of red blood cells can be shaped as elliptocytes , if above this it is considered abnormal.
Tue, 21 Jan 2020
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Internal Medicine Specialist 's  Response
Hello,

Above mentioned question is about thalasemia minor. Well thalesemia minor manifests as old mild anemia which is microcytic hypochrmic anemia. The red cell count (RCC) is usually normal or above the normal range in thalasemia trait. It won't cause any change in platelet configurations mild anemia related shortness of breath not responding to iron supplements. Hemoglobin electrophoresis is est done to diagnose this disease and is always done just once in life. Patient should know about his thalasemia trait status to avoid recurrent investigation of his anemia. The other parameters of platelets as mentioned may be discussed with a hematologist to get a further insight in this blood picture.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Muhammad Faisal Bacha, Internal Medicine Specialist
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What Are The Symptoms Of Thalesimia Trait?

Hello, Above mentioned question is about thalasemia minor. Well thalesemia minor manifests as old mild anemia which is microcytic hypochrmic anemia. The red cell count (RCC) is usually normal or above the normal range in thalasemia trait. It won t cause any change in platelet configurations mild anemia related shortness of breath not responding to iron supplements. Hemoglobin electrophoresis is est done to diagnose this disease and is always done just once in life. Patient should know about his thalasemia trait status to avoid recurrent investigation of his anemia. The other parameters of platelets as mentioned may be discussed with a hematologist to get a further insight in this blood picture. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Muhammad Faisal Bacha, Internal Medicine Specialist