Thanks for your question on Healthcare Magic. I can understand your concern. No need to worry for side effects by inhalers. Actually inhalers are very safe in long term use. They act locally and directly on lungs without going to blood. So inhalers don t act on other organs like kidney, heart, liver etc. So no systemic side effects by inhalers. You should also rinse your mouth after inhaler use to prevent oral complications. Also do pulmonary rehabilitation (deep breathing exercises and chest physiotherapy) for better symptomatic relief. So don t afraid of long term inhaler use. They are safe. Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.