Hello there, I can understand your concern. PCOS is a very common condition in which ovulation does not occur every month because of which one may have delayed periods and other problems. Meprate is a medicine which has the hormone called progesterone which is not enough in PCOS women due to absence of ovulation. That is why it is suggested to be taken at the end of the cycle just so that you get a bleed every month. If you do not take the medicine you may get delayed and irregular periods. Other than that there is no other role of Meprate. Its ok to take Meprate for the duration that you have been taking as it is only for 5 days in a month and if you dont take it then you have unopposed estrogen in your body which may do you little more harm than being on Meprate. So overall Meprate for 5 days in the cycle is safe to use. Its ok to take Meprate unless if you are planning to conceive or have already conceived. Hope this helps. Take care.