Hi Thanks for your query. Noted the history about your daughter and understood the concerns. Waking up with big stomach indicates that there is a gaseous distension as most probable cause. Other causes can be fluid called ascites or intraperitoneal pathology such as peritonitis. Hence I would advise your daughter the following in such a situation: Rush to Er for clinical evaluation and examination. X-ray of abdomen in standing position. Ultrasonography of abdomen. Tests of blood, urine and stool. Get the correct diagnosis to have a proper management. If there is an intestinal infection she may need a course of an antibiotic, metronidazole and probiotics. If there is any surgical cause, it will be treated accordingly. Take Care Regards Dr. T Chandrakant, General Surgeon