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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Remedy For ISADH

I have had ISADH, for a long time. My nephrologist believes it s from head injuries I sustained over my lifetime. I met with a new nephrologist today, as my previous one left the group. I am confused and concerned, because I don t fully understand this disorder and am told to restrict my water intake to no more than 4, 8 ounce glasses of water a day. We also talked about using pedialyte, Gatorade, Co-Co Nut water, and Almond Milk, as part of this fluid intake. Do I still heavily salt my food? And worst cast scenario, she said I could get brain swelling. Please, if any of you docs can shed further information, and relieve some of my anxiety please do. Thank you. Virginia (Jenna) West
Fri, 14 Oct 2016
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Nephrologist 's  Response
Please don't salt your food. What happened to you is similar to adjusting the house temperature with a thermostat. Our normal body sodium us between 135 to 145 meq/dl. It is maintained at that level by a complex interplay of hormones and Add or anti diuretic hormone is the most important among them. You have an inappropriately high ADH level,that is inappropriate to your body sodium level. The normal or low sodium that u have is sensed by the body as inappropriately high and body fails to suppress the ADH release that ought to have taken place at such low sodium level. So if u take high salt body is just going to retain more water and your blood sodium level will not improve. Best practical way is to restrict water. Next best thing is to use oral/intranasal ADH analog called desmopressin. Either way since your Nephro judged it is due to trauma, it will stick with you for for the rest of your life. So adapt.
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Suggest Remedy For ISADH

Please don t salt your food. What happened to you is similar to adjusting the house temperature with a thermostat. Our normal body sodium us between 135 to 145 meq/dl. It is maintained at that level by a complex interplay of hormones and Add or anti diuretic hormone is the most important among them. You have an inappropriately high ADH level,that is inappropriate to your body sodium level. The normal or low sodium that u have is sensed by the body as inappropriately high and body fails to suppress the ADH release that ought to have taken place at such low sodium level. So if u take high salt body is just going to retain more water and your blood sodium level will not improve. Best practical way is to restrict water. Next best thing is to use oral/intranasal ADH analog called desmopressin. Either way since your Nephro judged it is due to trauma, it will stick with you for for the rest of your life. So adapt.