thanks for asking few questions When was first noticed? *Has it increased in size since then? Any recent increase in size? *Do you have any breathing difficulty/ swallowing difficulty or any voice change? *Any history of weight loss/palpitations/ tremors/diarrhea? *Any associated weight gain/ hairloss/ tiredness/ constipation? *Any history of recurrent fever / thyroid pain/ eye pain / bulging eye ball/ tiredness? *Periods- is it regular? *How is your quality of life? *Any family history of thyroid disease/ goiter or thyroid malignancy? *Are you diabetic/ hypertensive? first of all treatment for hypothyroidism is only required if TSH is more than 10 and you don t just increase dose with symptoms but only with increased TSH values kindly taper the dose to check whether you need the drug currently approved weight loss drugs by FDA 1) tab orlistat taken orally it decreased fat absorption from gut. Average weight loss is 3-4kg per month if the person s diet predominantly fat based. 2) inj. liraglutide it s a GLP 1 analogue approved once a day injection taken , it decreased appetite. average weight loss 4-5 kg in guidelines. But in my experience I have seen 10 kg in one month