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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Prolonged seizures. Administered lorazepam and midazolam. Will it have side effects on children?

I am a School Nurse in CA. We have recently rec'd an order for an 8 yr old student to be administered buccal lorazepam for prolonged seizures. I have found some research, I'm not sure lorazepam is FDA approved for this route, especially for kids? What kind of training should we have prior to administration? The research seems to indicate faster absorption than rectal Diastat with fewer side effects - I.e. Less respiratory compromise, fewer admissions, less need for intubation, etc. We are not opposed to giving off label Meds but we do want to know what we are getting into first. Thanks for any assistance you can provide. We have also had a recent order for IN midazolam, We cannot locate anyone to provide training and it is not FDA approved. The prescribing MD has simply sent us a protocol from the Internet...
Fri, 25 Oct 2013
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HI
Thank for asking to HCM
Lorazepam and other such drugs which belongs to Benzodizepine group given in emergency in fit, seizures, convulsion, for to stop the tonic colonic movements, but once the episode overs then this drug have got no role, but the underlying cause has to be treated accordingly in most of the cases Epilepsy is the major cause of seizures and in such case the drug of choice is Carbamezepine, hope this answer will help you have nice day.
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Prolonged seizures. Administered lorazepam and midazolam. Will it have side effects on children?

HI Thank for asking to HCM Lorazepam and other such drugs which belongs to Benzodizepine group given in emergency in fit, seizures, convulsion, for to stop the tonic colonic movements, but once the episode overs then this drug have got no role, but the underlying cause has to be treated accordingly in most of the cases Epilepsy is the major cause of seizures and in such case the drug of choice is Carbamezepine, hope this answer will help you have nice day.