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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is The Stiffness In Legs And Pain Related To Daptomycin Infusion Treatment?

i get a reacuring case of cellulitis,edema in my legs and feet,it seems to come back on a once a month basis.i am recieving i v daptomycin infusion treatment once daily this time.although the swelling is almost all gone it seem this time was the worst.my legs and feet hurt to the bone,and are like stone,not really able to move them{pointing toes}just wondering if all this stiffness and pain is related to the infection {swelling up 30 + pounds. over night},or the meds?will my legs and feet be normal again,because now they feel like they need to be amputated!p.s a couple new symptoms this time:high fever {105.9}.,memory loss,major heel pain,veins rose to the surfase,and this time i got an ulcer,and when we popped it,blood came out of the ulcer, but also came out of a completely random spot,two inches away from the ulcer,every time we squeezed the ulcer,it would come out of the same random spot.total water loss is 32 pounds in 5 days!alot of peeing.still have 10 more days of i v daptomycin.any answers would be greatly appreciated.sincerly,angela rivera.a.k.a.walking like egor in st.augustine.florida.p.s.s. heard salt water is goog?should i go to the beach.or stay out of the sun,my legs and feet already look sunburned!!!!!
Thu, 1 Dec 2016
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Orthopaedic Surgeon 's  Response
hi
its ok that daptomycin is helping.
the important thing to find out is whether underlying bone marrow too is infected.this can be found on xrays,bone scan for any osteomyelitis which may require surgical saucerisation,debridement drainage and marrow infusion of antibiotics after culture senstivity test to identify causatavi microbe and to which antibiotic its very responsive
secondly fungal infection of bone or soft tissues should also be tested for as well as any anerobic infection which require more specific therapies,oral antifungals like flucanazole,metronidazole etc.
certain botlinum infections should be ruled out too
your doctor may be aware of this and maybe thorough in approach to management systematically
best wishes
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Is The Stiffness In Legs And Pain Related To Daptomycin Infusion Treatment?

hi its ok that daptomycin is helping. the important thing to find out is whether underlying bone marrow too is infected.this can be found on xrays,bone scan for any osteomyelitis which may require surgical saucerisation,debridement drainage and marrow infusion of antibiotics after culture senstivity test to identify causatavi microbe and to which antibiotic its very responsive secondly fungal infection of bone or soft tissues should also be tested for as well as any anerobic infection which require more specific therapies,oral antifungals like flucanazole,metronidazole etc. certain botlinum infections should be ruled out too your doctor may be aware of this and maybe thorough in approach to management systematically best wishes