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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Treat Persistent Itchy Hives?

I think I had an allergic reaction to Keflex, after I was taking it for 12 days. I broke out in severe hives and was in the ER three times this past weekend. I was given Prednisone (which they stopped, because it was driving me craxy), Benadryl, and Pepcid. When I went back again they did another dose of Benadryl and Peopcid, and an Ativan. The third time, I was given Epinephrine, Benadryl, Pepcid and Xanax. I was sent home and told to continue the Benadryl/Pepcid routine. I am on day five since I last took the antibiotic, and I still have very itchy hives everywhere. What should I do?
Tue, 18 Oct 2022
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General & Family Physician 's  Response
Hello,

You should avoid taking anything that aggravates your symptoms, food or medicine. Take care of your hygiene. Take regular bath and do not use perfumed beauty products. Always wear soft cotton clothes that are not tight-fitting. Do not touch, scratch or pick the hives. It may cause spread or worsening of the symptoms. Apply a soothing anti-itch lotion or cream like Prax lotion, any lotion or cream containing Pramoxine or a cream containing menthol.

It will can give you relief from the itch. Taking antihistamine will give you relief. This medication can help control the itch and swelling. Take it at bed time. If the hives are resistant, you need a stronger antihistamine, get clinically examined by a dermatologist, you may be prescribed Doxepin. You may require a repeat treatment with corticosteroids. When hives are severe, prednisone can reduce the inflammation and itch.

When antihistamines fail to work, Omalizumab is given, an injectable medication to treat resistant, chronic hives. Other treatment is phototherapy. Your dermatologist may give you medicines to calm your immune system like Cyclosporine or Hydroxychloroquine. Stay connected to your dermatologist.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Nupur K., General & Family Physician
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How To Treat Persistent Itchy Hives?

Hello, You should avoid taking anything that aggravates your symptoms, food or medicine. Take care of your hygiene. Take regular bath and do not use perfumed beauty products. Always wear soft cotton clothes that are not tight-fitting. Do not touch, scratch or pick the hives. It may cause spread or worsening of the symptoms. Apply a soothing anti-itch lotion or cream like Prax lotion, any lotion or cream containing Pramoxine or a cream containing menthol. It will can give you relief from the itch. Taking antihistamine will give you relief. This medication can help control the itch and swelling. Take it at bed time. If the hives are resistant, you need a stronger antihistamine, get clinically examined by a dermatologist, you may be prescribed Doxepin. You may require a repeat treatment with corticosteroids. When hives are severe, prednisone can reduce the inflammation and itch. When antihistamines fail to work, Omalizumab is given, an injectable medication to treat resistant, chronic hives. Other treatment is phototherapy. Your dermatologist may give you medicines to calm your immune system like Cyclosporine or Hydroxychloroquine. Stay connected to your dermatologist. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Nupur K., General & Family Physician