thank you.there are some side effect of these drugs particularly the medrol & duonase nasal spray.prolonged use of the spray may cause fungal infection of the mouth & throat and hoarseness of voice.the prolonged use of medrol may cause poor density of bone,hypertension,diabetes,muscle weakness,increased chance of infection and many others.but it is not proved that these drug cause fertility problem in men.you are to use these drugs for your problem.so try to limit their use and avoid adverse condition which aggravate your sinusitis.