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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Elevated CK Levels At 3000. Unable To Do Any Step Up, Curbs But Able To Walk. All Tests Normal. Opinion?

Hello, I am a 45 year old women with an elevated CK level. At last check, 1 week ago my level was at 3000, yes that is 3000 not 300. It has been high since May and been raising ever since. My doctors can't seem to figure out what is wrong with me. they have tested, biopsied, and tested some more, and have no answers. they say I shouldn't be able to even walk, but I am . I can't do stairs, and any step up is difficult, curbs included.
What do you think?
Thu, 12 Dec 2013
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General & Family Physician 's  Response
Hello,
Thanks for the query to H.C.M. Forum.
C K (40-150 U/L) i.e.creatine phosphokinase (CK) in you case it is 3000 U/L.
So high level may be due to .
1 Skeletal muscular disease ,including muscular dystrophy,myopathies, and polymyositis.
2 Electrical cardioversion,
3 hypothyroidism
4 stroke
5 skeletal muscle damage due to trauma , convulsions and prolonged immobilities .
An important drawback of total C K measurement is its lack of specificity as may elevated 5-6 times ( very steep hike ) even due to an intramuscular injectionfor example .
In my opinion mere elevation of C K is not a diagnostic finding until complete history is not known.
So please upload all clinical as well test reports over this site for evaluation of diagnosis.
Good luck.
Dr. HET
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Elevated CK Levels At 3000. Unable To Do Any Step Up, Curbs But Able To Walk. All Tests Normal. Opinion?

Hello, Thanks for the query to H.C.M. Forum. C K (40-150 U/L) i.e.creatine phosphokinase (CK) in you case it is 3000 U/L. So high level may be due to . 1 Skeletal muscular disease ,including muscular dystrophy,myopathies, and polymyositis. 2 Electrical cardioversion, 3 hypothyroidism 4 stroke 5 skeletal muscle damage due to trauma , convulsions and prolonged immobilities . An important drawback of total C K measurement is its lack of specificity as may elevated 5-6 times ( very steep hike ) even due to an intramuscular injectionfor example . In my opinion mere elevation of C K is not a diagnostic finding until complete history is not known. So please upload all clinical as well test reports over this site for evaluation of diagnosis. Good luck. Dr. HET