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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Long Time Use Of Morphine Has Side Effects?

Hi. In the past two years, I have had two surgeries to remove a disc herniation. The herniation (L4/L5) had been severly pinching my nerve. My last operation was 12 months ago, but I m still dealing with nerve pain. I also fractured the anterior process of L4. I have tried epidural and nerve root block shots. Neither worked to relieve the pain. I have also tried Gabapentin, Lyrica, and Cymbalta (all prescribed for nerve pain). I m on morphine for the pain and would like to know if long term use has negative side effects.
Mon, 27 Feb 2017
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Internal Medicine Specialist,  's  Response
Side effects of long-term morphine:
CV: Hypotension; orthostatic hypotension; bradycardia; tachycardia; palpitations. CNS: Lightheadedness; dizziness; drowsiness; sedation; euphoria; dysphoria; elirium; disorientation; incoordination. DERM: Sweating; pruritus; urticaria. E&ENT: Blurred vision; miosis. GI: Nausea; vomiting; constipation; abdominal pain. GU: Urinary retention or hesitancy. RESP: Respiratory depression; apnea; respiratory arrest; laryngospasm; depression of cough reflex. OTHER: Tolerance; psychological and physical dependence with chronic use; pain at injection site; local irritation and induration following SC use.
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Does Long Time Use Of Morphine Has Side Effects?

Side effects of long-term morphine: CV: Hypotension; orthostatic hypotension; bradycardia; tachycardia; palpitations. CNS: Lightheadedness; dizziness; drowsiness; sedation; euphoria; dysphoria; elirium; disorientation; incoordination. DERM: Sweating; pruritus; urticaria. E&ENT: Blurred vision; miosis. GI: Nausea; vomiting; constipation; abdominal pain. GU: Urinary retention or hesitancy. RESP: Respiratory depression; apnea; respiratory arrest; laryngospasm; depression of cough reflex. OTHER: Tolerance; psychological and physical dependence with chronic use; pain at injection site; local irritation and induration following SC use.