Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
179 Doctors are Online

Can taking Trazodone, Gabapentin and Duloxetine create a false positive for Lorazepam?

User rating for this question
Excellent
Answered by

General & Family Physician
Practicing since : 1991
Answered : 2763 Questions
Question
Hi my name is XXXXXXX I take trazodone, gabapentin and duloxetine HCL DR, with oxycodon-acetaminophen7.5-325 witch I have to drug test for. I was just told my test came back showing I have taken lorazepam. this is not the first time for this either. now after years of treatment they are talking about stop writing the oxycodon. I have never taken lorazepam before or really knew what it was until now. Im a liver transplant patient with back and bone issues. I do take other meds. but the first three mentioned make me question if one or two of them could be causing the false positives. at first she believed me but its getting old and I understand her position. Thank you for your time. Please Help XXXXXXX
Tue, 22 May 2018 in Brain and Spine
 
 
Answered by Dr. Bonnie Berger-Durnbaugh 3 hours later
Brief Answer:
Information

Detailed Answer:
Hello XXXXXXX

With increased urine testing, these false positives are becoming an increasing problem, because the basic test is not that accurate as you see.

I looked up several scientific articles on what can cause a false positive urine screen for benzodiazepines. Benzodiazepines are the class of medication that lorazepam is in.

The only thing that came up repeatedly as giving a false positive was the SSRI antidepressant sertraline, and also a particular NSAId (similar to ibuprofen).

So what to do: If the urine screen is inaccurate, the next step would be to get the more accurate GC-MS test done. I recommend you ask them to do this.

I'm sorry I couldn't pin point one of your medications with a research article to take to your doctor to back it up, but I can say that standard urine screens have their limitations and the next step is GC-MS.
Above answer was peer-reviewed by
 
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Drug/Medication
Medical Procedures
Medical Topics

The user accepted the expert's answer

Ask a Neurologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor