Hi, Yes, Rcinex tablets can affect sperm count in some cases. Rcinex is a combination medication that contains two drugs, rifampicin and isoniazid, which are used to treat tuberculosis. While these medications are effective in treating TB, they can sometimes cause side effects, including a decrease in sperm count. However, it is important to note that not all men who take Rcinex will experience a decrease in sperm count, and the extent of the decrease can vary from person to person. Other factors, such as age, lifestyle habits, and underlying medical conditions, can also affect sperm count. If you are trying to conceive and are concerned about your husband s low sperm count, it is important to speak with a healthcare provider. They can evaluate your husband s medical history, perform a physical exam, and order tests to determine the cause of the low sperm count. Depending on the cause, they may recommend treatment options such as medications, lifestyle changes, or assisted reproductive techniques to improve your chances of conceiving. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician