Amphetamine is a stress hormone. Inhalers are also stress hormones, so that does seem a bit odd. The paradoxical effect of a stimulant calming people down is quite common especially in drug dependence. Being on a blood pressure medicine means someone is NOT going to tolerate stress hormones. They are going to increase blood pressure which is already elevated. Signs of heart disease often include indigestion, nausea, panic. So... seeing that a person is not having a heart attack would be a first step. Psychological treatment of addiction which often includes issues of panic would also be useful in general. This particular patient is complex.