Hello, Cipralex may indeed cause blood glucose disorders and blood pressure disorders although both are rare. It may cause both hypo- and hyper- glycemia (the effect cannot be individually predicted) and both hypo- and hyper- tension. Such side effects occur in less than 1% of patients taking 20mg of Cipralex. It has to be even less likely in patients who have been taking it for a year without any side effects. Perhaps your doctor should try to identify other potential causes for your problems. Weight gain and sedentary lifestyle are inciting factors for hyperglycemia, although genetics play a major role in it - some individuals will never develop diabetes no matter how fat they become, others will experience hyperglycemia even when they stay lean. The same factors are important for hypertension as well. Salt consumption is another important factor in this regard. Checking your glucosylated hemoglobin would be recommended. High glucosylated hemoglobin may indicate that treatment for diabetes might be necessary... Regarding your blood pressure. Measuring your blood pressure (at least twice each time) for at least one week will give your doctor a better idea about it. 24-hour blood pressure monitoring (Holter) may be even more accurate in detecting blood pressure issues. So in conclusion, I don t believe that these symptoms are caused by Cipralex - although I can t 100% exclude it. An investigation is required to determine the extent of these issues and whether treatment is required or not. I wouldn t recommend any change to your regimen without discussing the matter with your doctor first. Consequently, I wouldn t recommend any other anti-anxiety medication. A rate of less than 1% for side effects is perfect for any drug and doctors almost never assume that side effects are caused by such a drug - they first have to eliminate all other potential causes. I hope I ve answered your question. Please let me know if you need further assistance. Kind Regards, Dr Panagiotis Zografakis Internal Medicine Specialist