Hello dear, After going through your history, I believe you have some genuine concern and I will try to help you out of this situation. The lump in your throat as per my expertise is due to reflux of acid from your stomach to the throat for which you have been given the particular medications you mentioned. H/O smoking, stress, faulty food habits also add onto this situation. Normally there is a valve at the junction of food pipe and stomach which prevent reflux, but factors like stress, excess smoking or consumption of coffee, tea, alcohol and many other factors lead to weakening of the valve which leads to reflux and the food pipe and throat gets burned repeatedly. Thus the area is not healing normally and this gives a sense of lump in throat. This takes a long time to heal and requires patience. Spitting or clearing the throat repeatedly will not improve the condition. In my clinic so to deal with this condition, I advise my clients life style modification as well as medication. Life style modifications include: 1.Weak up early and have 1 litre of Luke warm water ( Seems difficult, but will be in habit in a week) 2.Avoid coffee, tea, alcohol, smoking 3.Avoid spicy and oily foods 4. Take frequent small meals ( While eating the more the stomach distends, the more the acid secreted). 5. Have a brisk walk of 15 minutes after meals, walk after dinner is a must. 6. Very importantly, maintain a gap of 2 hours between dinner and going to bed. If you follow this within one month all your symptom of esophagitis will vanish. If you continue, never such situation will arise. Now the medication part, I advise my clients proton pump inhibitors like Omeprazol for a couple of weeks along with Lycopene capsules for better healing. I hope I could solve your query. Please do not hesitate to clarify more doubts for the same situation. Thank you for the way you are in my life. Dr Ipsit Panda