• question-icon

    What is the difference between Armour thyroid and Synthroid?

Posted on Tue, 11 Jul 2017 in Thyroid Problem and Hormonal Problems
Question: compare and contrast armour thyroid and synthroid base on drug interaction,efficacy,safety cost and expected outcome
Answered by Dr. Mirjeta Guni 3 hours later
Brief Answer:
About synthroid and armour thyroid:

Detailed Answer:
Hello and thank you for asking!
Armour Thyroid (desiccated porcine thyroid gland) and Synthroid (levothyroxine) are used as replacement therapy for thyroid hormone when the thyroid is under-active, nonfunctioning, or has been all or partly surgically removed.
The controversy over whether to use synthetic versions of thyroid hormone (Synthroid, Levoxyl, et al.) versus natural forms (Armour Thyroid) is better stated: “whether to use T4 alone or a T3 and T4 combination.”
A disadvantage of Synthroid is that some patients do not feel quite as well on T4 alone as they do on T3/T4 combinations. This is thought to be because not all tissues have the ability to convert T4 to T3 equally, such as brain tissue. In order to compensate for this, physicians may over medicate patients with T4 in order to compensate for this conversion problem.
Armour Thyroid was the only treatment for hypothyroidism for about 50 years, but it was found that the amounts of T3 and T4 varied greatly from batch to batch.
Eventually, synthetic T4 (Synthroid) was being produced and widely used because it did not have similar problems of standardization in common with the naturally derived Armour Thyroid.
So, Armour thyroid is used in specific cases, when the FT4 and FT3 can not be corrected by synthroid.
It costs more than synthroid, is not as safety as it ( hyperthyroidism is more difficult to be prevented by using armour). Regarding to drug interactions, it is the same with both preparations.
Hope i have answered your query.
Kind regards,
Above answer was peer-reviewed by : Dr. Nagamani Ng
Answered by
Dr. Mirjeta Guni


Practicing since :2006

Answered : 2309 Questions


The User accepted the expert's answer

Share on

Recent questions on  Levoxyl

doctor1 MD

I have been tired and sluggish with headaches for the last several days. I wake up tired. I am on imitrex for migraines and have had to take 1...

doctor1 MD

I was diagnosed with hypothyroidism earlier this year (late last year). I have been on three different types of thyroid medicine because the first...

doctor1 MD

I have been waking up after being asleep 5-6 hours. There is a dull ache right under my breasts on both sides- sort of a discomfort, not pain- I am...

doctor1 MD

I had my thyroidectomy in 2007 due to papillary cancer. I m 5 -7 and 165 pounds now (normally 145lbs) I m on levoxyl 125mcg, paxil, lithium,...

doctor1 MD

What can I do to decrease the time it takes for me to orgasm? I am currently taking testorone gel, levoxy for my thyroid , vitamin d and niacin for...

doctor1 MD

I am on Cipro for a UTI and I take Wellbutrin 300 MH. levoxyl .036 daily. I was extremely nauseous all day yesterday. I took a Pheregan at 5:00pm...

Get personalised answers from verified doctor in minutes across 80+ specialties

167 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Questions Answered By Dr. Mirjeta Guni
  • Q - What causes blurred vision, digestive issues and dizziness when...

  • Q - What causes weight gain and heat intolerance while on Synthroid,...

  • Q - Suggest treatment for weight gain when diagnosed with adrenal fatigue

  • Q - What causes hyperthyroidism?

  • Q - What are the side effects of long term intake of Aspirin?

  • Q - What do anxiety and palpitations and TSH level of 3.0 indicate?

  • Q - Suggest the ideal dosage for vitamin D supplement

  • Q - What causes increased weight gain with abdominal pain?

  • Q - Suggest treatment for insomnia and dizziness in a hypertensive person

  • Q - What are the possible effects of switching from Humalog to Novolog?