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What Does This Blood Report Indicate?

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Posted on Thu, 23 Jun 2016
Question: Sir I am XXXXXXX XXXXXXX 24 year old.my rbc count 6.27 with poikilocytosis and anisocytosis and presently I suffer with pcos.my dheas count 622 microgram / dl .sir what is condition
Symtoms.frequenty water intake poly urea.weight 64 kg
doctor
Answered by Dr. Anil Parth Desai (39 hours later)
Brief Answer:
hi i would recommend the following.

Detailed Answer:
Hi XXXXXXX
Thank you for your query.
Looking at your blood report with low hemoglobin, high rbc count and low mcv i am suspecting a hemoglobinopathy of milder type exactly known as thalassemia.

My first advice would be to do a HPLC test or a HB electrophoresis test to determine the condition.

Your PCOS is largely unrelated to this condition and it requires separate attention and treatment.
There is nothing to worry as many people have this condition and lead a normal life. Diagnosis is important for your kids in future.
I hope this helps mam.
Let me know if you have any other concern mam.
Sincerely,
DR PARTH DESAI

Above answer was peer-reviewed by : Dr. Prasad
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Follow up: Dr. Anil Parth Desai (6 hours later)
Why my dheas level 615 microgram/dl and I suffer with pcos.what should be condtion that dheas level high...
doctor
Answered by Dr. Anil Parth Desai (2 hours later)
Brief Answer:
Hi I would recommend the following.

Detailed Answer:
Dear Mam,

Thank you for your reply.

Regarding PCOS I assume that it is diagnosed with confirmation using the various other test including a pelvic ultrasound.

DHEA-S is a type of androgen that is predominantly secreted by adrenal gland. In your age of 24 years its higher limit of normal is 38 micrograms/dl. So a value of 615 is definitely high. Modest elevations of DHEA-S is also seen in PCOS and can go as high as 500. But values of 600 are reached unusually. So in that scenario, it is advisable to look for other causes of elevated secretion of DHEA-S. The most likely site then is to check for Adrenal gland and do a CT scan of abdomen (non contrast) to see if the adrenal glands are normal. High DHEAS can be seen in cushings disease, adrenal tumors, rarely ovarian tumors and PCOS. Also a low dose dexamethasone suppression test may be done to rule out cushing disease. But for that a detailed examination and other clinical features needed to be viewed.
If you are having lot of polyuria and lot of water craving that can be seen in diabetes or impaired glucose tolerance. This condition is seen in both adrenal problems as well as PCOS. So it is important to rule out adrenal problem.

I hope this helps mam.
Let me know if you any other concerns or questions and I will try my best to solve it.
Sincerely,
Dr Parth Desai
Above answer was peer-reviewed by : Dr. Yogesh D
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Follow up: Dr. Anil Parth Desai (26 hours later)
Thnk u sir given for rply
Sir polycythemia related to adaranal or sickell cell anemia
doctor
Answered by Dr. Anil Parth Desai (4 minutes later)
Brief Answer:
hi i would recommend following.

Detailed Answer:
Dear mam,

Thank you for your reply.
Your blood report does not look like polycythemia. Although rbc count is high hemoglobin is slightly low, ruling out polycythemia. Also MCV is low making a possibility of thalassemia trait or iron deficiency likely more likely thalassemia trait. Sickle cell anemia also less likely as it would have caused you trouble in young age with lot of pain and other problems. Also rbc count is never high in sickle cell anemia
The dheas elevation needs to be addressed separately and as i said it may need an imaging study of adrenal gland and a midnight cortisol level check.
I hope it helps mam.
Please let me know if any concern or question.
Sincerely,
Dr Parth Desai
Above answer was peer-reviewed by : Dr. Naveen Kumar
doctor
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Follow up: Dr. Anil Parth Desai (36 hours later)
Thank u for rply
Sir my last question is if any chances of cushing syndrom.
doctor
Answered by Dr. Anil Parth Desai (4 minutes later)
Brief Answer:
hi i would recommend the following

Detailed Answer:
Dear mam,
Thank you for your query.
Yes as I mentioned in my first answer cushing can be a possibility and we have seen rare cases where cushing and PCOS may exist together. Hence my recommendation is to get a screening test by a midnight- cortisol test or a dexamethasone suppression test to rule out cushing's disease. Elevated DHEAS can be seen in cushing's especially in the ones where problem is in pituitary gland causing overactivity of pituitary gland. So a screening test may be needed.

I hope this helps ma'm.
Please let me know if you have any other question or concern.
Sincerely,
Dr Parth Desai
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Sonia Raina
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Answered by
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Dr. Anil Parth Desai

Pathologist and Microbiologist

Practicing since :2009

Answered : 593 Questions

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What Does This Blood Report Indicate?

Brief Answer: hi i would recommend the following. Detailed Answer: Hi XXXXXXX Thank you for your query. Looking at your blood report with low hemoglobin, high rbc count and low mcv i am suspecting a hemoglobinopathy of milder type exactly known as thalassemia. My first advice would be to do a HPLC test or a HB electrophoresis test to determine the condition. Your PCOS is largely unrelated to this condition and it requires separate attention and treatment. There is nothing to worry as many people have this condition and lead a normal life. Diagnosis is important for your kids in future. I hope this helps mam. Let me know if you have any other concern mam. Sincerely, DR PARTH DESAI