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What Do These Histopathological Findings Indicate?

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Posted on Tue, 17 Nov 2015
Question: Picture in keeping with keratosis without dysplasia no malignancy seen?please explain the attach file photo also
doctor
Answered by Dr. Prof. Kunal Saha (2 hours later)
Brief Answer:
Explanation given

Detailed Answer:
Thanks for asking on HealthcareMagic.
I have gone through the attachment. It seems to be the histopathological findings from a post operative sample of the front and back portions of the tongue. Our body is made of different types of tissues and they in turn are made of various types of cells. The cells are so differentiated that the cellular organization of one type of tissue differs from another. Thus, the composition of skin is different from that of the liver. When there is loss of cellular organization and clear distinction is no longer present, it is called dysplasia. Dysplasia can subsequently lead to cancer. Such a dysplastic change is not present in the tissue sample obtained from the resected tongue. The changes that are seen, are nothing but thickening of the upper and outer layer. Such thickening is called keratosis due to the deposition of keratin.
Hope that clarifies your query.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Prof. Kunal Saha (15 hours later)
Parakeratosis will heal or not?squamous epithelial hyperplasia is itdangerous? This is about my tongue doc
doctor
Answered by Dr. Prof. Kunal Saha (2 hours later)
Brief Answer:
It is not dangerous.

Detailed Answer:
Parakeratosis or squamous epithelial hyperplasia is not dangerous in itself. Nevertheless, it is difficult to remove. You have to get the opinion of a skin specialist.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Prof. Kunal Saha (2 hours later)
Thanks doc do i have an underlying health problems because of this findings?
doctor
Answered by Dr. Prof. Kunal Saha (8 minutes later)
Brief Answer:
Underlying health problems are not mandatory

Detailed Answer:
Smoking is the commonest cause of such parakeratosis. In your case it seems to be of the harmless variety and is not a cause of concern. But there could be other possibilities like the ones mentioned on:
XXXX
(sorry for the technical nature of the document)
Another possible cause is friction
XXXX
Regards
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Prof. Kunal Saha

General & Family Physician

Practicing since :1954

Answered : 4467 Questions

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What Do These Histopathological Findings Indicate?

Brief Answer: Explanation given Detailed Answer: Thanks for asking on HealthcareMagic. I have gone through the attachment. It seems to be the histopathological findings from a post operative sample of the front and back portions of the tongue. Our body is made of different types of tissues and they in turn are made of various types of cells. The cells are so differentiated that the cellular organization of one type of tissue differs from another. Thus, the composition of skin is different from that of the liver. When there is loss of cellular organization and clear distinction is no longer present, it is called dysplasia. Dysplasia can subsequently lead to cancer. Such a dysplastic change is not present in the tissue sample obtained from the resected tongue. The changes that are seen, are nothing but thickening of the upper and outer layer. Such thickening is called keratosis due to the deposition of keratin. Hope that clarifies your query. Regards