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What Do My Blood Tests And Pelvic/abdominal Ultrasound Scan Test Reports Indicate?

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Posted on Mon, 27 Jul 2015
Question: My 11 ur old daughter underwent blood tests and pelvic/abdominal ultrasound. A .3 cm cyst was seen in gall bladder, poly cystic ovaries (severe), occult blood of 1+ in urine and high level of bilirubin in liver panel. What can this mean?
doctor
Answered by Dr. Archana Verma (1 hour later)
Brief Answer:
It seems that your daughter is suffering from Endometriosis

Detailed Answer:
Hi
Welcome to the HCM

I HAVE GONE THROUGH YOUR QUESTION. It seems to be due to endometriosis in your daughter.
I would recommend you to go for a complete evaluation by gynaecologist.
They may advice you for
-A complete blood cell (CBC) count with differential to help differentiate pelvic infection from endometriosis as well as assess the degree of blood loss.

-Urinalysis and urine culture if urinary tract infection (UTI) is in the differential diagnosis.

-serum cancer antigen 125 (CA-125) test-although levels may be elevated in advanced cases, but the results are useful as prognosticators of treatment outcome. However, normal posttreatment values do not mean that endometriosis is absent. Thus, the test lacks adequate sensitivity or specificity to be of clinical value.

-A diagnostic test based on the detection of autoantibodies against Thomsen-Friedenreich (T) antigen (Gal beta1-3GalNAc) bearing proteins appears promising. The sensitivity and specificity of the test are 80%.

-Another office test is the marker CCR1. The expression of the blood-borne marker CCR1 mRNA in peripheral blood leukocytes is significantly higher in women with endometriosis compared with unaffected women.

Also, MRI will be of great value.

The dependence of endometriosis on the woman's cyclic production of menstrual cycle hormones provides the basis for medical therapy. Medications currently recommended include gonadotropin-releasing hormone (GnRH) agonists, progestins, oral contraceptive pills, and androgens. Each of these interrupts the normal cyclic production of reproductive hormones. There are some data supporting the use of aromatase inhibitors for refractory or recurrent endometriosis.

Hopefully this will be helpful.
Take care


Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
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Follow up: Dr. Archana Verma (3 hours later)
How Can this occur even though my daughter has low WBC count and not started her period? Do i need to look at cancer testing?
doctor
Answered by Dr. Archana Verma (8 minutes later)
Brief Answer:
Its just a possibility.

Detailed Answer:
Hi

Endometriosis and PCOD are just possibility based on the findings till now. Anything definitive can be said only after complete body examination by gynaecologist and tests that I had suggested earlier.
Yes, cancer antigen testing is important but it can be done later if we come to a definitive diagnosis of endometriosis. It helps in prognostication.

Hopefully I have answered your question. For further questions, I Will be happy to help you out. Else, you may close the discussion, rate the answer and write a review.

Take care
Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
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Follow up: Dr. Archana Verma (5 days later)
She's more likely to start her period according to a Dr.
doctor
Answered by Dr. Archana Verma (8 hours later)
Brief Answer:
Multiple cysts in ovary may be seen at menarche

Detailed Answer:
Yes,
it may be possible that your child is going to have her first period. Ovaries appear multicystic at this stage. But jaundice and other findings needs evaluation.
Take care
Note: For further queries related to your child health, Talk to a Pediatrician. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Archana Verma

Pediatrician

Practicing since :2006

Answered : 1129 Questions

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What Do My Blood Tests And Pelvic/abdominal Ultrasound Scan Test Reports Indicate?

Brief Answer: It seems that your daughter is suffering from Endometriosis Detailed Answer: Hi Welcome to the HCM I HAVE GONE THROUGH YOUR QUESTION. It seems to be due to endometriosis in your daughter. I would recommend you to go for a complete evaluation by gynaecologist. They may advice you for -A complete blood cell (CBC) count with differential to help differentiate pelvic infection from endometriosis as well as assess the degree of blood loss. -Urinalysis and urine culture if urinary tract infection (UTI) is in the differential diagnosis. -serum cancer antigen 125 (CA-125) test-although levels may be elevated in advanced cases, but the results are useful as prognosticators of treatment outcome. However, normal posttreatment values do not mean that endometriosis is absent. Thus, the test lacks adequate sensitivity or specificity to be of clinical value. -A diagnostic test based on the detection of autoantibodies against Thomsen-Friedenreich (T) antigen (Gal beta1-3GalNAc) bearing proteins appears promising. The sensitivity and specificity of the test are 80%. -Another office test is the marker CCR1. The expression of the blood-borne marker CCR1 mRNA in peripheral blood leukocytes is significantly higher in women with endometriosis compared with unaffected women. Also, MRI will be of great value. The dependence of endometriosis on the woman's cyclic production of menstrual cycle hormones provides the basis for medical therapy. Medications currently recommended include gonadotropin-releasing hormone (GnRH) agonists, progestins, oral contraceptive pills, and androgens. Each of these interrupts the normal cyclic production of reproductive hormones. There are some data supporting the use of aromatase inhibitors for refractory or recurrent endometriosis. Hopefully this will be helpful. Take care