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What Causes Severe Headache And Stupefied Feeling After Taking Flexeril And Cymbalta?

Posted on Mon, 12 Oct 2015

Question: I took flexeril and I am on Cymbalta. both prescribed. my head is killing me and I feel spacy. should I be worried?

Answered by Dr. Ajay Panwar (11 minutes later)

Brief Answer:
Tell a few details.

Detailed Answer:
Hi XXXX,
Thanks for being on healthcaremagic.com.
I am Dr.Ajay Panwar,a neurologist,here to answer your query.

I would surely like to be of help but I need to know a few details beforehand-
1)Since when you are taking flexeril and Cymbalta?
2)Since when you are having headache?
3)Do you mean to say that both these medicines together,are somehow responsible for your headache?Please make your query,a little more clearer.
4)Is your headache persistent or episodic?If episodic,how many episodes in a day?What is the time period for which each episode lasts?

Please follow-up with details so that I can answer this well.

Regards
Dr.Ajay Panwar,
MD,DM(Neurology)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Ajay Panwar (15 minutes later)

I was prescribed Cymbalta about 6 weeks ago. I take 60 mg 1x per day. I was prescribed flexeril a year ago for tension to help me sleep. 10mg. I rarely take it. In fact, I took one last night for the first time in several months. I didn't know that they don't react well together. My head has been hurting since I woke this morning. shooting pain behind my eye and around whole right side.

Answered by Dr. Ajay Panwar (12 minutes later)

Brief Answer:
Serotonergic overactivity

Detailed Answer:
Hi XXXX,
Thanks for being in follow-up and providing details.

Both of the medicines if taken together,may cause serotonergic overactivity or full blown-serotonin syndrome.I think,your symptoms are probably resulting from the same mechanism.Don't ever take these two medicines together.These symptoms should improve in a few hours.However,if the severity of symptoms increase,please rush to an emergency room.

Hope that I have answered your query.If you have some further questions,I shall be glad to answer else please close the thread,rate it and write a review as your rating will be of help to me.

Regards
Dr.Ajay Panwar,
MD,DM(Neurology)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Ajay Panwar (3 minutes later)

My doctor didn't tell me any of the possible reactions to Cymbalta. Thank you for the help

Answered by Dr. Ajay Panwar (3 minutes later)

Brief Answer:
Flexeril with Cymbalta may cause serotonin syndrome.

Detailed Answer:
Hi XXXX,
Thanks for being in follow-up.

Serotonin syndrome is a known side effect of flexeril and cymbalta,taken together.

Hope that I have answered your query.If you have some further questions,I shall be glad to answer else please close the thread,rate it and write a review as your rating will be of help to me.

Regards
Dr.Ajay Panwar,
MD,DM(Neurology)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar