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Does Vicks NyQuil interact with Trazodone?

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Internal Medicine Specialist
Practicing since : 1999
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Question
Can I take trazodone & Vicks NyQuil
Fri, 11 May 2018 in Medicines and Side Effects
 
 
Answered by Dr. Panagiotis Zografakis 17 minutes later
Brief Answer:
you'd better avoid the combination

Detailed Answer:
Hello,

Vicks NyQuil (all formulations as there are many of them) contains dextromethorphane. This substance may interact with trazodone and cause the serotonin syndrome which is a potentially fatal complication. Thankfully it's not a frequent complication but it's too serious to ignore. So in conclusion you'd better avoid taking both drugs...

Kind Regards!
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