Brief Answer: Nervigenic agents + multivitamin & multiminerals Detailed Answer: Hello, Thanks for your query. Regarding the symptoms as mentioned in your post, kindly let us know about the following: 1. Any history of injury or trauma to the leg or lower back? 2. Sensation of twitching can be due to poor neuro-muscular co-ordination secondary to systemic illness. Is there is significant past history of systemic disease like Diabetes, Hypertension, Thyroid disorder, etc. ? 3. Any recent history of Stress, improper nutrition & lack of sleep? 4. Any history of prolonged intake of certain medications? 5. Habit of smoking or alcohol consumption? If your answer to the above mentioned questions is NO, then the symptoms can be attributed to either inadequate hydration status & electrolyte imbalance of the body or dietary deficiencies of certain nutrients like Iron, Calcium, Vitamin D, Vitamin B 12, Folic acid, etc. which help in blood formation & nerve conduction. Symptomatic relief can be obtained by intake of nervigenic agents (like Vitamin B6, Vitamin B 12, Folic acid) as well as multivitamin & multimineral supplements including iron, calcium & Vitamin D needs to be added in your diet. If symptoms still persist, kindly consult a Neurologist & get a complete Neurological examination done. Certain investigations like complete blood count, serum electrolyte estimation, fresh estimation of blood pressure & blood sugar levels, lipid profile & nerve conduction studies will be helpful to rule out any pathological cause for the symptoms. There is no need to worry, you will be fine. Till then, maintain adequate hydration & proper nutrition status, exercise regularly and avoid stress. Wishing you a Good Health. Please let me know if I need to clarify further. Take care.

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